By clicking “Accept All Cookies”, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. View our Privacy Policy for more information.

nordicBrainEx

Clinical Neuroimaging Software for Functional MRI

Clinical Neuroimaging Software for Functional MRI

NNL Basic fMRI Solution

  • MR compatible 40” LCD monitor - InroomViewingDevice
  • MR image and stimulus synchronization device - SyncBox
  • Stimulus presentation and workflow software - nordicAktiva
  • Patient response collection device - ResponseGrip
  • Stimulus presentation PC - Microsoft Surface Pro

NNL Advanced fMRI Solution

  • MR compatible 40” LCD monitor - InroomViewingDevice
  • MR image and stimulus synchronization device - SyncBox
  • Stimulus presentation and workflow software - nordicAktiva
  • Patient response collection device - ResponseGrip
  • Stimulus presentation PC - Microsoft Surface Pro
  • nordicBrainEx post-processing software - full license
  • Analysis PC

To Guide Surgeons During Neuronavigation

BOLD activation maps and DTI fiber groups can be exported to the neuronavigation systems to guide surgeons in their approach during surgery.

Assists Neuroradiologists with Treatment Follow-up

Advanced perfusion analysis allows neuroradiologists to assess treatment response, particularly:
1. Distinguish true from pseudoprogression
2. Distinguish true from pseudoresponse.

Assists Neuroradiologists in Diagnosis

Advanced perfusion analysis can be used for
1. Differential diagnosis
2. Suggestions of glioma grade &
histological sub-type.
3.Outcome and survival predictions

Improved clinical productivity

1. Clinical Workflow
2. User-friendly Interface
3. Automated Protocols
4. Fast analysis

nordicBrainEx

No items found.

Features

Reporting Feature

Save results, images and snapshots in a report format for ease of presentation.

No Special Hardware or Software Required

Runs on standard Windows platform.

Vendor Neutral

DICOM compatible and capable of analyzing data from all major MRI vendors.

Flexible Output Formats

Saving of parametric maps, 3D snapshots or animations to various file formats or directly to PACS.

Export Results to PACS and Neuronavigation Systems

Easy communication with PACS and other remote entities for retrieving data for analysis and for sending results.

Robust Co-registration of Functional with Structural MR Images

Functional MR images are automatically co-registered with 2D/3D structural images. Resulting maps can be used as overlays over structural images for accurate visualization.

Flexible Visualization and Analysis Options

Unlimited combination of overlays and underlays - combine BOLD fMRI, DTI, DSC perfusion and DCE overlays in same view.

Module-based Post-processing and Analysis

BOLD fMRI, DTI, Perfusion (DSC), DCE Modules which can be used either independently or in combination.

Technical Specifications

No items found.

Modules

BOLD fMRI module

BOLD fMRI is used to highlight small magnetic susceptibility changes in the human brain in areas with altered blood-flow resulting from neuronal activity. The BOLD fMRI analysis module can be used to generate and visualize activation maps from acquired BOLD fMRI time series, using a general linear model. Preprocessing includes co-registration of BOLD images with structural MR images, motion correction, slice-timing correction, Gaussian smoothing and high-pass temporal filtering. In the BOLD fMRI module, several conditions can be displayed in the same view, both in 2D and 3D, and the BOLD threshold can be adjusted interactively. VOI-tools can be used to inspect the time-intensity curves for quality assessment. Results can be exported for neuronavigation or saved to PACS.

DTI module

Diffusion analysis is used to visualize local water diffusion properties from the analysis of diffusion-weighted MRI data. Fiber tracking utilizes the directional dependency of diffusion to statistically model the white matter structure in the brain. In the DTI module, diffusion data with at least 6 directions can be used to calculate the diffusion tensor and produce diffusion output parameter maps such as ADC (mean diffusivity), FA (fractional anisotropy), Trace, eigenvalue maps etc. Pre-processing includes co-registration of tensor data with structural MR images, and motion and Eddy current corrections. Diffusion gradient information can be automatically extracted from the DICOM header or specified manually. DTI tractography is automatically displayed in 3D view, and multiple volumes/regions of interest can be used to define selected fiber groups and explore connectivity. Fiber groups can be presented in 2D/3D and exported to neuronavigation or saved to PACS.

Perfusion module

Dynamic susceptibility contrast imaging (perfusion MRI) is based on the analysis of tissue signal change following a bolus injection of a Gadolinium-based contrast agent, providing information about blood vessel structures and characteristics. The perfusion analysis includes co-registration of DSC images with structural MR images, normalization, leakage correction and vessel removal. The analysis is fast and generates cerebral blood volume (CBV), cerebral blood flow (CBF), mean transit time (MTT), time-to-peak (TTP), leakage and vessel mask output maps. Tissue response curves can be viewed from any region in the perfusion maps, together with histogram information.

DCE module

Dynamic contrast enhanced imaging (DCE-MRI) is based on the analysis of tissue signal change following a bolus injection of a Gadolinium-based contrast agent, enabling analysis of tissue permeability parameters, thus providing information about vascular permeability and intra- and extravascular volume. The DCE analysis employs two compartment modelling to generate output maps such as area under the curve (AUC), volume transfer constant (Ktrans), rate constant (Kep), plasma volume (Vp), fractional volume (Ve) and time to peak (TTP).

The MPR viewer displays perfusion and permeability maps, fiber tracking, and BOLD fMRI data together for extensive patient evaluation.

Contact us

Reach out to us if you're interested to learn more about this product, or get a live demonstration.

Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.