Advanced MRI Perfusion Software

nordicICE couples a perfusion package and a permeability analysis package. With these modules a large range of physiologically relevant parameters related to tissue perfusion and capillary permeability can be addressed both qualitatively and semi-quantitatively using state-of-the-art methods.

With nordicICE Perfusion Module the user can create high-quality perfusion maps from dynamic contrast enhanced MRI (T1 or T2/T2* weighted) in seconds. The combination of a user-friendly interface, myriads of options and possibilities, state- of-the-art methods and fast processing times ensure maximum productivity without loss of quality.

nordicICE is regulatory cleared for clinical applications and offers additional modules for BOLD fMRI and Diffusion/DTI analysis.

DSC Perfusion

Fast generation of perfusion maps: Blood volume (CBV), Blood flow (CBF), Mean Transit Time (MTT), Time to Peak (TTP) or Delay (SVD), Leakage (Ktrans), Brain Mask, Vessel Mask.
State-of-the-art deconvolution techniques, choice of manual or fully automatic selection of arterial input function, automated calculation of leakage map when the BBB is disrupted (leakage map - Ktrans), vessel removal algorithm for increased accuracy in evaluation of maps. Create normalized CBV maps. Combine perfusion and diffusion imaging for stroke evaluation.

DCE Perfusion

Quantitative maps: intra-extravascular leakage, extra-intravascular reflux, extravascular-extracellular space, plasma volume fraction.
Qualitative maps: area under curve, time to peak, peak enhancement, wash-in/wash-out rates